Table 1. Oligonucleotides targeted to the MDR1 gene and scrambled/mismatched controls.

Name	Target	Sequence	Chemical property
5995	AUG start codon of MDR1	5′-CCA TCC CGA CCT CGC GCT CC-3′	PS
10 221	Scrambled control of 5995	5′-CAC CAC CCC CCT CGC TGG TC-3′	PS
13 758	AUG start codon of MDR1	5′-CCA TCC CGA CCT CGC GCT CC-3′	PS, 2′-O-ME and PS
13 753	Scrambled control of 13 758	5′-CAC CAC CCC CCT CGC TGG TC-3′	PS, 2′-O-ME and PS
GS1954	AUG start codon of MDR1	6′-CCA TCC CGA CCT CGC GCT CC-propanediol-4′	HNA
GS1955	Mismatched control of GS1954	6′-CCA TAC CAA CAT CAC GCT CC-propanediol-4′	HNA
GS1956	AUG start codon of MDR1	6′-CCA TCC CGA CCT CGC GCT CC-propanediol-4′	PS, HNA
GS1957	Mismatched control of GS1956	6′-CCA TAC CAA CAT CAC GCT CC-propanediol-4′	PS, HNA
GS1962	AUG start codon of MDR1	6′-fl-CCA TCC CGA CCT CGC GCT CC-propanediol-4′	HNA
GS1964	AUG start codon of MDR1	6′-fl-CCA TCC CGA CCT CGC GCT CC-propanediol-4′	PS, HNA

PS, phosphorothioate internucleotide linkage; 2′-O-ME, 2′-O-methoxyethylribonucleoside; HNA, HNA with phosphodiester internucleotide linkage; fl: fluorescein.

Non-italic, phosphodiester; italic, phosphorothioate; bold, 2'-O-ME; underline, HNA.