Table 5. Comparison of demographic characteristics and clinical features of patients with metastatic KP-PLA vs. non-metastatic KP-PLA at a tertiary teaching hospital, Zhejiang University, mainland China, May 1994 to December 2015.
| Variables | Metastatic KP-PLA (n = 20) N (%) or mean ± SD | Non-metastatic KP-PLA (n = 169) N (%) or mean ± SD | P value |
|---|---|---|---|
| Mean age (years) | 62.7 ± 12.1 | 59.1 ± 13.1 | NS |
| Gender | NS | ||
| Male | 11 (55.0) | 104 (61.5) | |
| Female | 9 (45.0) | 65 (38.5) | |
| Origin of liver abscess | NS | ||
| Primary liver abscess | 14 (70.0) | 84 (49.7) | |
| Secondary liver abscess | 6 (30.0) | 85 (50.3) | |
| Number of abscess | NS | ||
| Solitary liver abscess | 17 (85.0) | 134 (79.3) | |
| Multiple liver abscesses | 3 (15.0) | 35 (20.7) | |
| Location of abscess | NS | ||
| Left hepatic lobe | 2 (10.0) | 32 (18.9) | |
| Right hepatic lobe | 17 (85.0) | 120 (71.0) | |
| ≥2 lobes | 1 (5.0) | 17 (10.1) | |
| Size of abscess | NS | ||
| Size ≤5 cm | 2 (10.0) | 34 (20.1) | |
| Size >5 cm | 18 (90.0) | 135 (79.9) | |
| Mean size (cm) | 7.3 ± 2.3 | 7.0 ± 2.5 | NS |
| Underlying disease | |||
| Diabetes mellitus | 13 (65.0) | 81 (47.9) | NS |
| Hypertension | 10 (50.0) | 62 (36.7) | NS |
| Fatty liver | 7 (35.0) | 54 (32.0) | NS |
| Hepatobiliary disease | 5 (25.0) | 83 (49.1) | 0.041 |
| Malignancy | 0 (0.0) | 15 (8.9) | NS |
| History of hepatobiliary surgery | 2 (10.0) | 46 (27.2) | NS |
| History of intra-abdominal trauma or surgery | 3 (15.0) | 51 (30.2) | NS |
| Method of abscess drainage | NS | ||
| Drainage not performed | 5 (25.0) | 18 (10.7) | |
| Drainage performed | 15 (75.0) | 151 (89.3) | |
| Clinical outcomes | |||
| Septic shock | 6 (30.0) | 22 (13.0) | NS |
| ICU admission | 9 (45.0) | 38 (22.5) | 0.028 |
| LOIS (days) | 11.7 ± 10.3 | 8.4 ± 13.1 | 0.040 |
| LOHS (days) | 20.7 ± 13.7 | 18.5 ± 13.1 | NS |
| In-hospital mortality | 4 (20.0) | 7 (4.1) | 0.019 |
Note: NS, not significant; PLA, Pyogenic liver abscess; KP-PLA, K. pneumoniae induced PLA; Metastatic KP-PLA, KP-PLA with extrahepatic infectious complications; Non-metastatic KP-PLA, KP-PLA without extrahepatic infectious complications; LOIS, Length of ICU stay; LOHS, Length of hospital stay.