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. 2004 Aug 9;101(33):11929–11936. doi: 10.1073/pnas.0403799101

Scheme 6.

Scheme 6.

Vancomycin: a synthetic target whose novel architecture afforded the opportunity to develop new chemistry, such as a triazene-driven method for bisaryl ether formation and a cross-metathesis reaction in water to form dimeric vancomycin analogs with activity greater than that of the natural product.