Table 2.

DWI metrics of the Gaussian mono-exponential and bi-exponential models as well as the non-Gaussian kurtosis model in tumours and non-tumorous (down- and upstream) parenchyma and their analysis of variance (ANOVA).

DWI metrics	Regions	Number of ROIs	Mean value	Standard deviation	P-value (ANOVA)
ADC (10−3 mm2/s)	Tumour	36	1.435	0.15	<0.0001
	Downstream	21	1.586	0.21
	Upstream	28	1.663	0.24
D (10−3 mm2/s)	Tumour	36	0.955	0.31	0.35
	Downstream	21	0.909	0.32
	Upstream	28	1.045	0.39
D* (10−3 mm2/s)	Tumour	36	17.76	17.66	0.63
	Downstream	21	22.35	21.38
	Upstream	28	17.63	19.29
f	Tumour	36	0.30	0.15	0.32
	Downstream	21	0.35	0.12
	Upstream	28	0.35	0.16
K	Tumour	36	1.070	0.16	0.15
	Downstream	21	1.091	0.19
	Upstream	28	1.003	0.17
DK (10−3 mm2/s)	Tumour	36	2.161	0.48	<0.001
	Downstream	21	2.685	0.49
	Upstream	28	2.752	0.72

Abbreviations: ADC = apparent diffusion coefficient, D = true diffusion coefficient, D* = pseudo-diffusion coefficient, f = perfusion fraction, K = kurtosis coefficient, D_K = corrected diffusion coefficient.