Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 20;40(12):1864–1874. doi: 10.1038/ijo.2016.146

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Macmillan Publishers Limited, part of Springer Nature.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Food intake-independent effects of C₁₂TPP in wild-type mice on a HFD at thermoneutrality. Time course of food intake (a) and body weight change relative to day 0 (b) of control, C₁₂TPP-treated mice and mice pair-fed with the treated group. Treatment and pair-feeding started on day 0 and finished on day 27. The values are the means±s.e.m. of six to seven mice per group. The effects for overlapping time points with the control were statistically analyzed with a repeated measures two-way analysis of variance (ANOVA): for both a and b (time: P<0.0001; treatment: P<0.0001; interaction P<0.001). The effects for overlapping time points for treated and pair-fed mice was statistically analyzed with a repeated measures two-way ANOVA for a: the food intake in pair-fed group was pre-defined and cannot be included in the ANOVA; for b (time: P<0.0001; treatment: P<0.0001; interaction P<0.001). *Significant differences between the pair-fed and control groups. #Significant differences between the pair-fed and treated groups. The difference between the control and treated groups is not shown. (c and d) Lipid and energy contents of feces. A lipid analysis (c) was performed on feces from the first 3 days of treatment and bomb calorimetry was used to estimate the energy (d) content of feces from 7 to 9 days of treatment. Bars represent the mean±s.e.m. of four to six mice per group. (e) Amount of feces produced during the first three days (1 to 3) and 7 to 9 days of treatment. Bars represent the mean±s.e.m. of five to six mice per group. The data were statistically analyzed with a repeated measures two-way ANOVA: (treatment: P<0.001; days ns; interaction ns). #Significant differences between the pair-fed and treated groups. (f) Total fecal energy per day of C₁₂TPP treatment. The fecal energy (as in d) was multiplied by the amount of feces (as in e) and this amount was divided by 3 days. Bars represent the mean±s.e.m. of five to six mice per group. The data were analyzed with Student's t-test and # indicates significant differences between the pair-fed and treated groups.