Figure 6. In vivo bioluminescent imaging analysis based on Saa3 promoter activity in mice.

(A) Transgenic mice carrying Saa3-luc were generated (Saa3-luc mouse). Saa3-luc mice were fed either ND or HFD for 8 weeks and 16 weeks, and subjected to in vivo bioluminescence analysis. (B) At the end of these 16 weeks, several types of tissue of Saa3-luc mice were isolated and subjected to the luciferase activity. The data (mean ± S.E.) are from a single experiment carried out (n = 3) and are representative of two independent experiments. *p < 0.05.