TABLE 3.

Study Participation [n (%)]

	Academic Centers	Community Centers
	(n = 1905)	(n = 1165)	P
Treatment phase
Completed	1020 (54)	634 (54)	0.64
Discontinued	885 (46)	531 (46)	0.64
Because of treatment failure	520 (27)	310 (27)	0.68
Because of adverse events	234 (12)	128 (11)	0.28
Because the patient did not wish to continue	63 (3)	45 (4)	0.42
Because of lost to follow-up	44 (2)	34 (3)	0.30
Because of noncompliance with protocol	18 (1)	13 (1)	0.65
Because of protocol ineligibility	4 (<1)	1 (0.1)	0.41
Administrative	2 (<1)	0	0.27
24-wk follow-up phase
Completed	1507 (79)	910 (78)	0.51
Discontinued	166 (9)	103 (9)	0.90
Because of lost to follow-up	101 (5)	62 (5)	0.98
Because the patient did not wish to continue	54 (3)	34 (3)	0.89
Because of noncompliance with protocol	5 (<1)	4 (<1)	0.69
Because of adverse events	6 (<1)	3 (<1)	0.78
Never entered follow-up phase	232 (12)	151 (13)	0.52