Table 1.
Demography and Distribution of Organ Failure, Organ Dysfunction, and Infection in Patients With Traditional Severe Sepsis and Sepsis-3. Patients Can Be Represented in Both Columns
| Variables | Traditional Severe Sepsis | Sepsis-3 | PValue |
|---|---|---|---|
| N = 131 | 96 | 109 | |
| Age, median | 78 | 80 | |
| 18–24 | 1 (1.0%) | 1 (0.9%) | |
| 25–34 | 1 (1.0%) | 0 | |
| 35–44 | 3 (3.1%) | 1 (0.9%) | |
| 45–54 | 3 (3.1%) | 1 (0.9%) | |
| 55–64 | 6 (6.3%) | 10 (9.2%) | |
| 65–74 | 22 (22.9%) | 25 (22.9%) | |
| 75–84 | 29 (30.2%) | 32 (29.4%) | |
| 85–94 | 29 (30.2%) | 36 (33.0%) | |
| ≥95 | 2 (2.1%) | 3 (2.8%) | |
| Comorbidities | |||
| None | 23 (24.0%) | 20 (18.3%) | |
| Heart disease | 30 (31.3%) | 40 (36.7%) | |
| Malignancy | 23 (24.0%) | 26 (23.9%) | |
| Asthma, COPD | 22 (22.9%) | 19 (17.4%) | |
| Diabetes mellitus | 18 (18.8%) | 22 (20.2%) | |
| Cerebrovascular disease | 17 (17.7%) | 22 (20.2%) | |
| Chronic renal failure | 10 (10.4%) | 11 (10.1%) | |
| Cirrhosis | 2 (2.1%) | 1 (0.9%) | |
| Immunodeficiency | 0 | 0 | |
| Connective tissue disorder | 9 (9.4%) | 11 (10.1%) | |
| Ward at Initiation of Antibiotis | |||
| Emergency Department | 65 (67.7%) | 67 (61.5%) | |
| Nonsurgical ward | 19 (19.8%) | 31 (28.4%) | |
| Surgical ward | 10 (10.4%) | 8 (7.3%) | |
| Intensive care unit | 2 (2.1%) | 3 (2.8%) | |
| Organ Dysfunction | |||
| Cardiovascular | 50 (52.1%) | 41 (37.6%) | .037 |
| CNS | 30 (31.3%) | 28 (25.7%) | |
| Hepatic | 0 | 7 (6.4%) | .015 |
| Renal | 29 (30.2%) | 37 (33.9%) | |
| Respiratory | 27 (28.1%) | 87 (79.8%) | <.01 |
| Hematologic | 7 (7.3%) | 11 (10.1%) | |
| Hypoperfusion | 24 (25.0%) | ||
| Chock | 7 (7.3%) | 4 (3.7%) | |
| Number of Organs Dysfunction | |||
| 1 | 49 (51.0%) | 40 (36.7%) | .038 |
| >1 | 47 (49.0%) | 69 (63.3%) | |
| Site of Infection | |||
| Respiratory tract | 40 (41.7%) | 55 (50.5%) | |
| Urinary tract | 17 (17.7%) | 19 (17.4%) | |
| Abdominal | 14 (14.6%) | 12 (11.0%) | |
| Skin or soft tissue | 7 (7.3%) | 5 (4.6%) | |
| Other | 18 (18.8%) | 18 (16.5%) | |
Abbreviations: COPD, chronic obstructive pulmonary disease; CNS, central nervous system.