Fig. 3.

Differences in fractional anisotropy between the three approaches. (A) Histograms of mean fractional anisotropy values using the single-fiber skeleton, whole skeleton and tractography approaches in acute or sub-acute mild traumatic brain injury (mTBI). (B) Boxplot of FA values in patients and controls yielded by three approaches: complete white matter skeleton, white matter skeleton restricted to single-fiber voxels and whole brain tractogram. (This graph was generated by GraphPad Prism version 7.0, GraphPad Software, San Diego, California, USA, www.graphpad.com).