Fig. 2.

Effects of rh5-HTTLPR genotype (l/l or l/s), rearing condition (MR or PR), and sex (male or female) on cortisol responses to acute stress in infant rhesus macaques. (A) Values listed are mean plasma levels of cortisol in μg/dl ± SEM determined at baseline (Stress –, 2 and 6 months) and after stress (Stress +,3,4, and 5 months). (B–D) Shown are serum cortisol levels for Basal-1 (B), stress (C), and Basal-2 (D) testing conditions. There were main effects of rearing condition and of rh5-HTTLPR genotype on cortisol. In addition, there was an interaction among sex, rearing condition, and rh5-HTTLPR, such that female PR l/s animals had lower levels of cortisol.