Table 2.
ANOVA Tests of Inter-Group Differences in Gene Expression in Relation to Survival.
| Gene | F-Ratio | P-Value |
|---|---|---|
| ASPH | 4.073 | 0.0272 |
| NOTCH1 | 4.028 | 0.0269 |
| JAGGED1 | 4.000 | 0.0275 |
| HES1 | 5.382 | 0.0093 |
| HEY1 | 3.610 | 0.038 |
| HIF-1α | 4.404 | 0.0199 |
Gene expression was measured by a Quantigene 2.0-based RNA hybridization assay (see Methods). Results were analyzed by 1-way ANOVA and the Tukey multiple comparisons post-test. F-ratios and P-values reflect variances with respect to short (<6 months) versus intermediate (7–23 months) or long-term (>24 months) survival. Results with significant inter-group differences are shown in Fig. 4.