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Triphasic and heterogenic P-EIM responses. SPR (a) and EIM (b) profiles of GPCR stimulation by 18 μM histamine in the first 350 s. Arrows indicate three phases (P1, P2, P3) of the profiles. Gray profiles represent the responses of individual cells, and black profiles are the averages of all the cells in the imaging field. The size of a single pixel is ∼0.97 μm2.
