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. 2004 Aug 24;2(9):e296. doi: 10.1371/journal.pbio.0020296

Figure 4. CR Increases the Life Span of Cells Overexpressing SIR2 .

Figure 4

(A) Neither deletion of FOB1 nor overexpression of SIR2 impact longevity in PSY316. Strains shown (and mean life spans) are PSY316 (21.1), PSY316 fob1Δ (20.7), and PSY316 SIR2-ox (21.7).

(B) Overexpression of SIR2 and CR increase life span additively in BY4742. Strains shown (and mean life spans) are BY4742 on 2% glucose (26.1), BY4742 on 0.05% glucose (31.8), BY4742 SIR2-ox on 2% glucose (34.6), and BY4742 SIR2-ox on 0.05% glucose (42.2).