Table 6. Comparison between the thermosensitive (study group 1) and silicone plug (study group 2) as regards microscopic features of conjunctival impression cytology before and after treatment.
Grading | Group 1 |
Group 2 |
||||
Baseline (n=45) | 3mo (n=45) | 6mo (n=45) | Baseline (n=45) | 3mo (n=39) | 6mo (n=24) | |
Cohesion power | ||||||
Grade 1 | 0.0 | 0.0 | 36.0 (80.0) | 0.0 | 0.0 | 7.0 (29.2) |
Grade 2 | 35.0 (77.8) | 35.0 (77.8) | 0.0 | 35.0 (77.8) | 29.0 (74.4) | 9.0 (37.5) |
Grade 3 | 10.0 (22.2) | 10.0 (22.2) | 9.0 (20.0) | 10.0 (22.2) | 10.0 (25.6) | 8.0 (33.3) |
Cell size | ||||||
-1 | 10.0 (22.2) | 10.0 (22.2) | 10.0 (22.2) | 10.0 (22.2) | 10.0 (25.6) | 8.0 (33.3) |
0 | 0.0 | 0.0 | 35.0 (77.8) | 0.0 | 0.0 | 5.0 (20.8) |
1 | 35.0 (77.8) | 35.0 (77.8) | 0.0 | 35.0 (77.8) | 29.0 (74.4) | 11.0 (45.9) |
N/C ratio | ||||||
1:3 | 0.0 | 0.0 | 16.0 (35.6) | 0.0 | 0.0 | 3.0 (12.5) |
1:4 | 18.0 (40.0) | 18.0 (40.0) | 11.0 (24.4) | 18.0 (40.0) | 14.0 (35.9) | 6.0 (25.0) |
1:5 | 17.0 (37.8) | 17.0 (37.8) | 8.0 (17.8) | 17.0 (37.8) | 15.0 (38.5) | 7.0 (29.2) |
1:6 | 4.0 (8.9) | 4.0 (8.9) | 4.0 (8.9) | 4.0 (8.9) | 4.0 (10.3) | 2.0 (8.3) |
1:7 | 6.0 (13.3) | 6.0 (13.3) | 6.0 (13.3) | 6.0 (13.3) | 6.0 (15.3) | 6.0 (25.0) |
Distribution of goblet cells (in 4 HPF) | ||||||
Absent | 10.0 (22.2) | 10.0 (22.2) | 4.0 (8.9) | 10.0 (22.2) | 10.0 (25.6) | 8.0 (33.3) |
Present | 35.0 (77.8) | 35.0 (77.8) | 41.0 (91.1) | 35.0 (77.8) | 29.0 (74.4) | 16.0 (66.7) |
Degree of keratinization | ||||||
Absent | 0.0 | 0.0 | 36.0 (80.0) | 0.0 | 0.0 | 7.0 (29.2) |
Mild | 10.0 (22.2) | 10.0 (22.2) | 9.0 (20.0) | 10.0 (22.2) | 29.0 (74.4) | 0.0 |
Moderate | 35.0 (77.8) | 35.0 (77.8) | 0.0 | 35.0 (77.8) | 10.0 (25.6) | 17.0 (70.8) |
Overall conjunctival impression cytology grading | ||||||
Grade 1 | 0.0 | 0.0 | 28.0 (62.2) | 0.0 | 0.0 | 14.0 (58.3) |
Grade 2 | 28.0 (62.2) | 28.0 (62.2) | 0.0 (0.0) | 28.0 (62.2) | 22.0 (56.4) | 0.0 |
Grade 3 | 17.0 (37.8) | 17.0 (37.8) | 17.0 (37.8) | 17.0 (37.8) | 17.0 (43.6) | 10.0 (41.7) |
HPF: High power field.
n (%)