Fig 4. Laboratory parameters recorded as adverse events.

All clinically significantly abnormal laboratory parameters are represented according to their severity. All were attributed to malaria infection. There were no significantly abnormal laboratory parameters recorded as AEs attributable to other causes. Of the 25 laboratory parameters that were recorded as AEs, 15 were abnormalities of LFTs, i.e. either an elevation of ALT or AST. The majority of laboratory AEs were moderate in severity with 2 mild and 9 severe. Abbreviations: LDH: lactate dehydrogenase; AST: aspartate aminotransferase; ALT: alanine amino transferase.