Table 1. Quality control levels used to evaluate method performance.
| Analytes | LLOQ (ng/mL) | LQC (ng/mL) | MQC (ng/mL) | HQC (ng/mL) | DQC (ng/mL) |
|---|---|---|---|---|---|
| Chlorpropamide | 500 | 1000 | 2500 | 3500 | 25000 |
| Glibenclamide | 125 | 250 | 1000 | 1500 | 10000 |
| Gliclazide | 50 | 125 | 500 | 750 | 5000 |
| Glimepiride | 125 | 250 | 1000 | 1500 | 10000 |
| Metformin | 250 | 500 | 2000 | 3000 | 20000 |
| Nateglinide | 500 | 1000 | 2000 | 3000 | 20000 |
| Pioglitazone | 250 | 500 | 1000 | 1500 | 1000 |
| Rosiglitazone | 125 | 250 | 500 | 750 | 5000 |
| Vildagliptin | 125 | 250 | 1000 | 1500 | 10000 |
LLOQ, lower limit of quantification; LQC, low quality control; MQC, medium quality control; HQC, high quality control; DQC, dilution quality control.