Table 1.
Membrane structural changes as a function of growth rate and cultivation technique
| STRUCTURE 1 | Continuous cultivation | Fed-batch cultivation | Comment | ||||
| Parameter | Low μ | Max/Min | High μ | Low μ | Max/Min | High μ | Min/Max values which correlate with μ = 0.3 h-1 |
| Phospholipids (%) | |||||||
| PE | 70 | 75 | 78 | 77 | n.p. | 77 | |
| PG | 16 | 18 | 15 | 12 | ** | 11 | Max value only in CC |
| CL | 8 | 7 | 7 | 12 | * | 12 | |
| PS | 7 | - | - | - | - | - | Compound not produced in FB |
| Fatty acids (%) | |||||||
| C14:0 | 3 | 1 | 2 | 3 | n.p. | 3 | Min value only in CC |
| C16:0 | 53 | 49 | 52 | 44 | * | 44 | Min value only in CC |
| C16:1 | 16 | 22 | 21 | 19 | 28 | 26 | Max value only in CC |
| C18:1 | 8 | 20 | 14 | 12 | 21 | 18 | Max value only in CC |
| C17:1 | 20 | 7 | 11 | 22 | 9 | 9 | Min value only in CC |
1Summary of the structural differences in continuous and fed-batch cultivation as a function of growth rate. Results compared to data from Shokri et al 2002. N.p.: max/min not present. CC: continuous cultivation, FB: fed-batch cultivation. * value is slightly decreased compared to the value at high μ. ** value is slightly increased compared to the values at high μ. A high growth rate refers to μ = 0.6 h-1 and a low growth rate to μ = 0.05 h-1.