Specificity and sensitivity. (a) nFTP sensors were functionalized with anti-tau-PS262 (sc-32828, Santa Cruz) and anti-β-Actin (ab13822, Abcam), and were employed to measure tau-PS262 and β-Actin proteins in different cell types after the cells were treated with isoflurane. The error bar comes from three measurements on the same cell. (b) LSPR shift at different concentrations of tau-PS262 solutions. 0.5, 1, 5, 10, 50, 100, 500 nM tau-PS262 (Santa Cruz, sc-32828p) in the cell culture medium (without FBS) were prepared, and sequentially tested. At each concentration, 1,000 spectra were measured. The nFTP was regenerated between two different concentrations.