TABLE 1.

Clinical Characteristics of Very Low-risk Wilms Tumor Patients Managed by Observation Alone Postnephrectomy Who Subsequently Relapsed

UPN	Age at Diagnosis (Months)	Tumor Weight at Diagnosis (Grams)	Histology at Diagnosis	ILN at Diagnosis	PLN at Diagnosis	Time to Relapse (Days)*	Site of First Relapse	Symptoms at Relapse	Chemotherapy	Radiotherapy
1	21	250	Mixed	None	None	68	Lung	No	DD4A	Whole lung
78	9	261	Blastemal	None	None	138	Lungs	No	DD4A	Whole lung
154	5	508	Blastemal	None	None	376	Retroperitoneum	No	DD4A	Flank
165	14	505	Blastemal	None	None	120	Lung	Yes	DD4A	Whole lung
399	10	271	Mixed	None	None	91	Retroperitoneum	No	DD4A	Flank
434	3	254	Blastemal	None	None	94	Right renal fossa	No	DD4A	Delayed Flank
450	15	178	Epithelial tubular	None	None	80	Contra lateral kidney	No	DD4A	Flank
476	12	252	Mixed	None	None	186	Right renal fossa/Lungs	No	DD4A	Flank/Whole lung
500	20	490	Mixed	Present-multiple	None	178	Abdomen	Yes	DD4A	Whole abdomen
508	5	270	Mixed	Present	None	1305	Lung	No	DD4A	No
756	13	540	Mixed	Present	None	107	Lung	No	DD4A	Whole lung
800	23	169	Mixed	Present	None	246	Retroperitoneum	Yes	DD4A	abdomen

^*Time to relapse from time of enrolment.

DD4A indicates vincristine, dactinomycin, doxorubicin × 24 weeks; ILN, intralobar, nephrogenic rests; PLN, perilobar nephrogenic rests; UPN, unique patient number.