Table 3.
Univariate Analyses and Multivariate analyses for Local Control of MPNST
| Variable | LC at 5y | LC P Value |
|---|---|---|
| Age, years | ||
| ≤ 65 | 84 | 0.75 |
| > 65 | 75 | |
| Sex | ||
| Male | 80 | 0.43 |
| Female | 87 | |
| NF-1 Status | ||
| Mutated | 83 | 0.57 |
| Non-mutated | 85 | |
| Site | ||
| Head & Neck | 90 | 0.61 |
| Trunk | 74 | |
| Upper Extremities | 85 | |
| Lower Extremities | 85 | |
| Tumor Size | ||
| > 5 cm | 82 | 0.56 |
| ≤ 5 cm | 83 | |
| Final Margin Status* | ||
| Positive/Uncertain | 72 | 0.01 |
| Negative | 95 | |
| Treatment Sequence | ||
| Postoperative RT | 84 | 0.94 |
| Preoperative RT | 86 | |
| RT Dose | ||
| ≥60 Gy | 83 | 0.90 |
| <60 Gy | 86 | |
| Neo or Adj. Chemo | ||
| Yes | 86 | 0.34 |
| No | 81 | |
Abbreviations: LC, local control; RT, radiation therapy
*
Significant on multivariate modeling.
Reported in-text.