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. 2016 Dec 6;24(12):2207–2216. doi: 10.1016/j.str.2016.10.005

Figure 2.

Figure 2

M2 Helix Bundle of 5-HT3R

The M2 helix bundle of 5-HT3R is shown embedded within a lipid (POPC) bilayer. The arrow indicates the ion permeation pathway and reaction coordinate (z) along which the ion and water PMFs are calculated.