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. 2016 Nov 15;419(2):348–356. doi: 10.1016/j.ydbio.2016.08.030

Fig. 2.

Fig. 2

Fgf10 and Fgfr2 are expressed during Steno's gland and MSG development. Trichrome stained sagittal sections of the distal Steno's gland (A) and at stage E14.5 of development. (B) At E14.5, Fgf10 expression is found throughout the mesenchyme beneath the maxillary sinus epithelium in the location of where the Steno's gland will branch, while Fgfr2 is expressed in the distal epithelial cells of the Steno's duct (C). At E16.5 the Steno's gland is undergoing continual branching (D). Fgf10 is expressed in the mesenchyme surrounding the distal gland buds (E) and Fgfr2 is evident in the distal epithelial cells of the Steno's gland end buds (F). (G) Trichrome stained sagittal section of the MSG primordium at E14.5. Fgf10 is expressed throughout the mesenchyme surrounding the MSG primordium at E14.5 (H) and Fgfr2 mRNA is detected in the maxillary sinus epithelium, of which the MSG buds (I). By E16.5 when the MSG is branching (J), Fgf10 is expressed in the mesenchyme surrounding the branching MSG end buds (K). By E16.5, Fgfr2 expression is lost from the maxillary sinus epithelium but found within the distal end buds of the MSG (L). Yellow line=Steno's gland; blue line=basement membrane of the maxillary sinus epithelium, red line=MSG; orange line=maxillary sinus lumen. Scale bar=100 µm.