Figure 2.

Alignment of PD-L1 amino acid sequence in eight mammalian species. The black-to-white color gradient indicates the degree of amino acid conservation among species, with black boxes indicating the most highly conserved sequence regions and white boxes indicating the most divergent regions for devil PD-L1. Dashes indicate gaps that have been introduced for best-fit multiple-sequence alignments. The putative extracellular domains, transmembrane domains, intracellular domains, and signal peptides are denoted by lines above the sequence.