. Author manuscript; available in PMC: 2017 Dec 1.

Published in final edited form as: Surg Pathol Clin. 2016 Dec;9(4):677–684. doi: 10.1016/j.path.2016.05.010

Table 2.

Identification of Cyst Type using Molecular Marker

Type of Cyst	Molecular Markers
	Any of these	Any of these	Senstivity (95% CI)	Specificity (95% CI)
	Present	Absent	Senstivity (95% CI)	Specificity (95% CI)
SCA	VHL chr3 LOH	KRAS GNAS RNF43 chr5p aneu chr8p aneu	100% (74–100%)	91% (84–95%)
SPN	CTNNB1	KRAS GNAS RNF43 chr18 LOH	100% (69–100%)	100% (97–100%)
MCN	None	CTNNB1 GNAS chr3 LOH chr1q aneu chr22q aneu	100% (74–100%)	75% (66–82%)
IPMN	GNAS RNF43 chr9 LOH chr1q aneu chr8p aneu	None	76% (66–84%)	97% (85–99.9%)

MPD = main pancreatic duct. chr = Chromosome. CI=confidence intervals. aneu = aneuploidy.