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. 2016 Nov 10;5:37–53. doi: 10.1016/j.ynstr.2016.11.002

Fig. 9.

Fig. 9

Effect of acute oxycodone on the distribution of DOR-SIG particles in CA3 and dentate hilar dendrites in CIS females. A, B. Representative electron micrographs show the distribution of DOR-SIG particles in hilar dendrites from a saline and oxycodone injected CIS estrus females. Examples of plasmalemmal (arrow with tail), near plasmalemmal (chevron) and cytoplasmic (arrow) DOR-SIG particles in dendrites are shown. Scale bars A, B = 500 nm. C. One hour after oxycodone (3 mg/kg, I.P.), the partitioning ratio of DOR-SIG particles significantly increases on the plasmalemma and significantly decreases near the plasmalemma of hilar dendrites in CIS estrus females (**p < 0.01). D. One hour after oxycodone, the percent of DOR-labeled dendritic spines contacted by mossy fibers approaches a significant increase (ˆp = 0.056). N = 3 rats per group; n = 50 dendrites (C) or mossy fibers (D) per rat.