Table 3.
Details of Malaria Parasite Detection by Microscopy
| RDT Positive |
Microscopy-Positive Patients |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| RDT Positive by CHW |
Geometric Mean Parasite Density/µL | |||||||||
| 1447 | 1860 | 862a | 1593 | Min | Max | |||||
| Overall | no. | No. | % | no. | No. | % | 6946 | 40 | 436 450 | P Value |
| Age group | ||||||||||
| <12 mo | 181 | 257 | 70.4 | 110 | 224 | 49.1 | 8783 | 40 | 436 450 | .227 |
| 12–23 mo | 393 | 503 | 78.1 | 250 | 429 | 58.3 | 6479 | 40 | 286 560 | |
| 24–35 mo | 311 | 397 | 78.3 | 177 | 334 | 53.0 | 7813 | 40 | 317 200 | |
| 36–47 mo | 341 | 422 | 80.8 | 196 | 361 | 54.3 | 7623 | 40 | 408 000 | |
| 48–59 mo | 220 | 279 | 78.9 | 128 | 243 | 52.7 | 4734 | 40 | 293 600 | |
| 60–72 mo | 1 | 2 | 50.0 | 1 | 2 | 50.0 | 36 935 | 36 935 | 36 935 | |
| Treatment group | ||||||||||
| RDT positive by CHW treated with ACTs | 1422 | 1422 | 100 | 798 | 1215 | 65.7 | 7707 | 40 | 436 450 | .013 |
| Rectal artesunate (danger signs) | 24 | 24 | 100 | 15 | 24 | 62.5 | 11 428 | 600 | 116 560 | |
| RDT negative (CHW) referred, no treatment | 0 | 7 | … | 0 | 4 | 0.0 | … | … | … | |
| RDT negative (CHW) not referred, no treatment | 1 | 407 | 49b | 350 | 1098 | 40 | 54 059 | |||
Abbreviations: ACT, artemisinin-based combination therapy; CHW, community health worker; RDT, rapid diagnostic test.
a Parasite density in cumulative percentages: <200 /µL, 5.8%; <500/µL, 12.3%; and <1000/µL, 17.2% patients.
b Ten of 49 (20.4%) and 20 of 49 (40.8%) children who recorded a false-negative RDT result had parasite density >20 000/µL and >3000/µL, respectively.