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. 2016 Dec 5;129(23):2853–2860. doi: 10.4103/0366-6999.194654

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Copyright: © 2016 Chinese Medical Journal

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Effect of siRNA-mediated knockdown of activator protein-1 on ultraviolet A-induced cathepsin L expression and enzymatic activity. siRNA transfection knocked down activator protein-1 expression (a), which reduced ultraviolet A-induced cathepsin L messenger RNA (b), protein (c), and activity (d). Data are from three independent experiments. *P < 0.05 versus control; ^†P < 0.05 versus ultraviolet A-treated control or ultraviolet A-nontargeting control. UVA: Ultraviolet A; CatL:Cathepsin L; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; C:Control; SP: SP600125; SB: SB203580; NC: Nontargeting control siRNA; siRNA:Small interfering RNA.