Table 1.

Characteristics of the included RCTs

Study, year	Setting	Definition of shorter and longer durations	Total number	Type of DES	P2Y12 inhibitor	Follow-up (months)
Shorter versus 12-month DAPT
SECURITY, 2016	International	Shorter: 6 months	429	2G	Clopidogrel	24
		Longer: 12 months			Prasugrel
OPTIMIZE, 2014	Brazil	Shorter: 3 months	1103	2G	Clopidogrel	12
		Longer: 12 months
RESET, 2012	Korea	Shorter: 3 months	292	1G	Clopidogrel	12
		Longer: 12 months		2G
EXCELLENT, 2012	Korea	Shorter: 6 months	550	1G	Clopidogrel	12
		Longer: 12 months		2G
12-month versus prolonged DAPT
REAL/ZEST-LATE, 2010	Korea	Shorter: 12 months	704	1G	Clopidogrel	24
		Longer: 24 months		2G
DAPT, 2014	11 countries	Shorter: 12 months	3391	1G	Clopidogrel	33
		Longer: 30 months		2G	Prasugrel

1G: First-generation; 2G: Second-generation; DES: Drug-eluting stent; RCTs: Randomized controlled trials; DAPT: Dual antiplatelet therapy.