Table 3. Passage number of primary cancer epithelial cells transduced with immortalizing genes compared with control cells.
| Primary culture | Immortalizing gene | Number of passages with transduction | Number of passages without transduction |
|---|---|---|---|
| BC22 P:5 | SV40LT | 6 | 12 |
| BMI-1 | 6 | ||
| SV40LT + BMI-1 | 4 | ||
| hEST2 | 5 | ||
| BC46 P:1 | SV40LT | 5 | 9 |
| BMI-1 | 3 | ||
| SV40LT + BMI-1 | 4 | ||
| hEST2 | 5 | ||
| BC49 P:1 | SV40LT | 5 | 9 |
| hEST2 | 10 | ||
| SV40LT + hEST2 | 10 | ||
| BC50 P:1 | SV40LT | 9 | 8 |
| hEST2 | 8 | ||
| SV40LT + hEST2 | 3 | ||
| BC51 P:1 | SV40LT | 3 | 8 |
| hEST2 | 8 | ||
| SV40LT + hEST2 | 3 | ||
| PC21 P:4 | SV40LT | 7 | 7 |
| PC38 P:1 | SV40LT | 7 | 8 |