Table 4.

Univariate and multivariate analyses for overall survival

	Univariate analysis
Factors	HR (95% CI)	p value
Age (years)
<50 (vs. ≥50)	1.20 (0.76–1.89)	0.436
Tumor origin
Bone (vs. soft tissue)	1.32 (0.77–2.27)	0.318
Primary site		0.633
Trunk (vs. extremities)	0.85 (0.43–1.68)	0.639
Retroperitoneum (vs. extremities)	0.65 (0.31–1.37)	0.259
Visceral (vs. extremities)	1.15 (0.56–2.35)	0.702
Histological subtype		0.002
UPS (vs. leiomyosarcoma)	1.24 (0.55–2.81)	0.608
Others (vs. leiomyosarcoma)	2.54 (1.46–4.42)	0.001
Prior chemotherapy		0.126
Second-line (vs. first-line)	1.38 (0.72–2.65)	0.332
Third-or-greater line (vs. first-line)	1.90 (1.00–3.62)	0.052
Response to GD
SD/PD (vs. CR/PR)	3.81 (1.37–10.55)	0.010
	Multivariate analysis
Factors	HR (95% CI)	p value
Age (years)
≥50 (vs. <50)
Tumor origin
Bone (vs. soft tissue)
Primary site
Trunk (vs. extremities)
Retroperitoneum (vs. extremities)
Visceral (vs. extremities)
Histological subtype
UPS (vs. leiomyosarcoma)
Others (vs. leiomyosarcoma)
Prior chemotherapy
Second-line (vs. first-line)
Third-or-greater line (vs. first-line)
Response to GD
SD/PD (vs. CR/PR)	3.99 (1.42–11.22)	0.009