Table 3.

Rates and trends in melanoma by site on body among non-Hispanic whites aged 15–49, SEER, 1992–2012

		Rate per 100,000	N*	%	Trend 1		Trend 2
					Year	APC	Year	APC
Male	Trunk	6.9	8,334	46.2	1992–2006	1.1*	2006–2012	−3.24*
	Head and neck	2.4	2,941	16.3	1992–2012	1.9*
	Upper extremity	3.0	3,674	20.4	1992–2012	1.2*
	Lower extremity	2.0	2,435	13.5	1992–2008	2.7*	2008–2012	−7.60
	Overlapping or NOS	0.6	667	3.7	1992–2012	−1.9*
Female	Trunk	6.3	7,366	33.0	1992–2005	3.9*	2005–2012	0.03
	Head and neck	1.6	1,816	8.1	1992–2012	2.1*
	Upper extremity	4.4	5,126	23.0	1992–2012	2.1*
	Lower extremity	6.5	7,592	34.0	1992–2006	3.7*	2006–2012	−2.97*
	Overlapping or NOS	0.4	433	1.9	N/A

APC=Annual percent change, calculated using Joinpoint Regression Program, available at http://surveillance.cancer.gov/joinpoint/.

NOS=Not otherwise specified.

^*denotes statistical significance (p<0.05).

N denotes the total number of cases included in the analysis for all years 1992–2012. The dataset includes cases diagnosed from about 13% of the US population.

Rates are per 100,000 persons and are age-adjusted to the 2000 U.S. standard population (19 age groups – Census P25–1130).

Trends and APC calculated using Joinpoint Trend Analysis Software.

Source for trend data: Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 13 Regs Research Data, Nov 2014 Sub (1992–2012) <Katrina/Rita Population Adjustment> - Linked To County Attributes - Total U.S., 1969–2012 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Surveillance Systems Branch, released April 2015, based on the November 2014 submission.