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. Author manuscript; available in PMC: 2016 Dec 9.
Published in final edited form as: Nano Lett. 2015 Aug 5;15(9):5696–5701. doi: 10.1021/acs.nanolett.5b01243

Figure 4.

Figure 4

(a) Examples of particle trajectories used for calculating the mean squared displacement (MSD). Diffusion coefficients obtained from linear fits of the first seven data points of the MSD are determined independently for diffusion in the cis- and trans-microchannels, displacements through the nanochannel are not considered (see SI for details). (b) Distribution of diffusion coefficient versus nanosphere radius measured for cis- (top) and trans-microchannel (bottom), the radius is determined on the basis of resistance pulse during translocation through the nanochannel. The fitting equation is D = b(r)a; for cis- and trans-microchannels the value of a is acis = −1.4 ± 0.3 and atrans = −0.9 ± 0.2.