Supplementary Table S3.
Statistical analysis of tmax of LY2157299 including all patients.
| Parameter | Formulation, 150 mg | N | Median (min, max) | Median difference RCD/RCS – HSWG (90% CI) |
|---|---|---|---|---|
| tmax (h) | HSWG | 14 | 1.00 (0.50, 3.08) | |
| RCD | 14 | 2.00 (0.50, 3.17) | 0.54 (0.00, 1.09) | |
| RCS | 14 | 2.00 (0.50, 3.00) | 0.00 (0.00, 0.71) |
Abbreviations: CI = confidence interval; HSWG = high- sheer wet granulation; max = maximum; min = minimum; RCD = roller compaction dry-milled; N = number of patients; tmax = time of maximum plasma drug concentration; RCS = roller compaction slurry-milled.