TABLE 3.

Transfer by transformation of erythromycin resistance determinants from VGS to S. pneumoniae R6

Donor	Donor phenotype	Donor gene(s)	Frequency of transformation	Transformant phenotype	Transformant gene(s)
S. mitis 130	M	mef(E), mel	1.5 × 10−7	M	mef(E), mel
S. mitis 143	M	mef(E), mel	3.0 × 10−7	M	mef(E), mel
S. mitis 147	M	mef(E), mel	7.8 × 10−7	M	mef(E), mel
S. mitis 183	M	mef(E), mel	5.3 × 10−7	M	mef(E), mel
S. mitis 220	M	mef(E), mel	1.1 × 10−7	M	mef(E), mel
S. mitis 208	cMLSB	erm(B)	3.3 × 10−9	cMLSB	erm(B)
S. oralis 47	M	mef(E), mel	6.7 × 10−7	M	mef(E), mel
S. oralis 288	M	mef(E), mel	1.7 × 10−6	M	mef(E), mel
S. oralis 296	M	mef(E), mel	2.1 × 10−7	M	mef(E), mel
S. salivarius 137	iMLSB	erm(B), mef(E), mel	1.1 × 10−7	M	mef(E), mel
S. salivarius 172	cMLSB	erm(B), mef(E), mel	2.0 × 10−6	M	mef(E), mel
G. haemolysans 70	M	mef(E), mel	1.7 × 10−7	M	mef(E), mel
G. haemolysans 78	M	mef(E), mel	1.9 × 10−6	M	mef(E), mel
G. haemolysans 79	M	mef(E), mel	6.3 × 10−6	M	mef(E), mel
G. morbillorum 95	M	mef(E), mel	1.7 × 10−7	M	mef(E), mel
G. morbillorum 256	M	mef(E), mel	8.9 × 10−8	M	mef(E), mel