TABLE 1.
Location (na) | % of isolates with mutations at codon for gene groupb:
|
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DHFR
|
DHPS
|
MDR
|
CRT
|
||||||||||||
51 | 59 | 108 | 164 | 436 | 437 | 540 | 581 | 613 | 86 | 184 | 1034 | 1042 | 1246 | 76 | |
Entosopia (31) | 94 | 100 | 100 | 0 | 3 | 94 | 81 | 0 | 0 | 90 | 100 | 100 | 100 | 100 | 100 |
Magadi (22) | 91 | 100 | 77 | 0 | 0 | 96 | 73 | 0 | 0 | 86 | 100 | 100 | 100 | 100 | 100 |
Kericho (38) | 92 | 100 | 97 | 0 | 0 | 74 | 66 | 0 | 0 | 68 | 100 | 95 | 100 | 95 | 92 |
Kisumu (34) | 97 | 100 | 91 | 0 | 27 | 41 | 65 | 0 | 0 | 35 | 100 | 100 | 97 | 35 | 82 |
n, number of samples tested.
DHFR, dihydrofolate reductase; DHPS, dihydropteroate synthase; MDR, multidrug resistance gene; CRT, chloroquine resistance transporter.