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. 2004 Sep;48(9):3598–3601. doi: 10.1128/AAC.48.9.3598-3601.2004

TABLE 1.

Percentages of mutations at specific codons within malaria drug resistance genes

Location (na) % of isolates with mutations at codon for gene groupb:
DHFR
DHPS
MDR
CRT
51 59 108 164 436 437 540 581 613 86 184 1034 1042 1246 76
Entosopia (31) 94 100 100 0 3 94 81 0 0 90 100 100 100 100 100
Magadi (22) 91 100 77 0 0 96 73 0 0 86 100 100 100 100 100
Kericho (38) 92 100 97 0 0 74 66 0 0 68 100 95 100 95 92
Kisumu (34) 97 100 91 0 27 41 65 0 0 35 100 100 97 35 82
a

n, number of samples tested.

b

DHFR, dihydrofolate reductase; DHPS, dihydropteroate synthase; MDR, multidrug resistance gene; CRT, chloroquine resistance transporter.