TABLE 6.
Bacteriological response outcomes for mice infected with ATCC 6303 and treated with moxifloxacin and levofloxacin
| Disease severitya | Moxifloxacin
|
Levofloxacin
|
||||
|---|---|---|---|---|---|---|
| No. with eradication/total (%) | Viable count in mice with no eradication (log10 CFU)
|
No. with eradication/total (%) | Viable count in mice with no eradication (log10 CFU)
|
|||
| Meanb | Range | Meanb | Range | |||
| Moderate | 31/31 (100) | 31/42 (74)c | 7.0 ± 1.5 | 4.3-8.9 | ||
| Severe | 24/27 (89) | 7.6 ± 0.4 | 7.0-7.9 | 9/17 (53)d | 6.6 ± 1.9 | 3.8-8.7 |
a
Moderate surface temperature of ≥32°C; Severe, surface temperature of <32 to >30°C.
b
Values are means ± standard deviations.
c
P = 0.05 compared with the value for the moxifloxacin group.
d
P = 0.01 compared with the value for the moxifloxacin group.