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. 2016 Dec 5;11:6485–6497. doi: 10.2147/IJN.S117184

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© 2016 Wang et al. This work is published and licensed by Dove Medical Press Limited

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(A) Flow cytometry histogram profiles of DOX florescence within HeLa cells and (B) quantitative analysis of mean fluorescence intensity when incubated with a series of particles for 6 h.

Notes: Data are represented as mean ± SD (n=3). *Statistical difference versus the DOX@HA-PL-MSNs group (P<0.05); **statistically significant difference versus the DOX@HA-PL-MSNs group (P<0.01).

Abbreviations: DOX, doxorubicin; HA, hyaluronic acid-functionalized; MSN, mesoporous silica nanoparticle; PL, pH stimuli-responsive lipid membrane; SD, standard deviation.