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. 2016 Dec 5;11:6485–6497. doi: 10.2147/IJN.S117184

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© 2016 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Confocal microscopy images of HeLa cells treated with the FITC-labeled HA-PL-MSNs, MSNs, and PL-MSNs, respectively.

Notes: Green fluorescence arises from FITC dyes that are conjugated to silica nanoparticles and red fluorescence shows the DOX intake in cells.

Abbreviations: DOX, doxorubicin; FITC, fluorescein-5-isothiocyanate; HA, hyaluronic acid-functionalized; MSN, mesoporous silica nanoparticle; PL, pH stimuli-responsive lipid membrane.