Table 3.

Cox proportional hazard models showing the association between self-reported pedal edema and incident congestive heart failure

	# of Events	Unadjusted Hazard Ratio (95%CI)	Model 1* Hazard Ratio (95%CI)	Model 2** Hazard Ratio (95%CI)	Model 3*** Hazard Ratio (95%CI)
Pedal Edema	184/4196	1.39(1.03–1.88) P value = 0.032	1.44(1.05–1.97) P value= 0.022	1.43(1.02–1.99) P value =0.038	1.27(0.94–1.79) P value = 0.166

Model 1* adjusted for age, gender and race/ethnicity

Model 2** = model1 + systolic BP, BP meds, diabetes mellitus, BMI, cigarette smoking status, baseline LVEF, LDL and HDL cholesterol, serum creatinine and urinary albumin level and antecedent myocardial infarction which occurred during the follow up.

Model # 3*** = model 2 + NT proBNP levels