FIG. 2.

Effects of R126638 (▴ and Δ) and itraconazole (▪ and □) on [¹⁴C]acetate incorporation into ergosterol by C. albicans. [¹⁴C]acetate, an azole antifungal, and/or DMSO was added immediately before inoculation. Cells were collected after 24 h of growth. The results are expressed as the percentage of radioactivity incorporated in desmethylsterols (ergosterol), 14-methylated sterols, and squalene. ▴ and ▪, ergosterol; Δ and □, 3,6-diol. Each symbol represents the mean of at least three experiments.