TABLE 1.

Deduced functions of ORFs.

ORF	Putative function	Size (no. of amino acids)	Homologues
			Gene	Deduced role	SM/ID of producta	Origin	GenBank nucleotide accession no.
1	Transport	417		Integral membrane ion antiporter	54/42	Amycolatopsis orientalis	AL078635
2	Regulation	934	pikD	Transcriptional activator	44/33	Streptomyces venezuelae	AF079139
3	Halogenase	547	pmC	Halogenase	59/43	Myxococcus fulvus	AF161185
4	PKS	2,057	epoD	PKS	42/32	Polyangium cellulosum	AF217189
5	PKS	3,112	mxaC	PKS	50/37	Stigmatella aurantiaca	AF319998
6	PKS	828	stiG	PKS	58/45	Stigmatella aurantiaca	AJ421825
7	Thioesterase	268	rifR	Thioesterase	44/32	Amycolatopsis mediterranei	AF040570
8	Flavin reductase	173	rebF	Flavin reductase	55/47	Lechevalieria aerocolonigenes	AJ414559
9	Adenylation enzyme	377	tycA	NRPSb adenylation domain	59/43	Brevibacillus parabrevis	P09095
10	Starter unit for biosynthesis	437	SCGD3.18c	BCDH E1 α subunit	73/61	S. coelicolor A3(2)	AL939117
11	Starter unit for biosynthesis	381	SCGD3.17c	BCDH E1 β subunit	84/77	S. coelicolor A3(2)	AL939117
12	Starter unit for biosynthesis	442	SCGD3.16c	BCDH E2 subunit	57/50	S. coelicolor A3(2)	AL939117
13	Starter unit for biosynthesis	628	SCAH10.35c	Oxidoreductase α subunit	89/86	S. coelicolor A3(2)	AL939127
14	Starter unit for biosynthesis	>210	SCD20.12c	Oxidoreductase β subunit	97/96	S. coelicolor A3(2)	AL939120

^aSM/ID, percent similarity/percent identity of amino acid sequences.

^bNRPS, nonribosomal peptide synthase.