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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: J Heterocycl Chem. 2015 Sep 18;53(6):1871–1877. doi: 10.1002/jhet.2501

Scheme 1.

Scheme 1

Reagents and Conditions: (i) 4-R-PhCH2Cl, K2CO3, Acetone, reflux, 8h (ii) N2H4. H2O 160°C, 5h (iii) ArCHO, EtOH, 60°C, 2h (iv) NaN3, DMSO, rt-50°C, 4h (v) NH4Cl, EtOH/H2O, Zn, reflux, 4h (vi) 10% Pd/C, H2, EtOH