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ELF and AC pharmacokinetic parameters in the 150- and 300-mg-dose groups
| Dose group | Parameter
|
||||
|---|---|---|---|---|---|
| Cmax (μg/ml) | Tmax (h) | Cmin (μg/ml) | AUC0-24 (μg · h · ml) | t1/2 (h) | |
| 150 mg | |||||
| ELF | 0.94 | 2.0 | 0.118 | 11.4 | 6.43 |
| AC | 12.7 | 8.0 | 2.88 | 160.8 | 10.0 |
| 300 mg | |||||
| ELF | 2.75 | 4.0 | 0.13 | 24.15 | 5.26 |
| AC | 55.4 | 6.0 | 6.66 | 636.2 | 11.6 |
