Table 2. Time to Peak, Peak Value, and Duration of Symptoms of Any Grade from Day 0 (Post Challenge) To Day 8 in Laboratory-Confirmed Infected Subjects.

Symptoms	Viral titre group
	1 TCID50	10 TCID50	100 TCID50
	N = 4	N = 6	N = 5
	Mean (SD)	Mean (SD)	Mean (SD)
Time to peak (days)	3.8 (0.96)	3.0 (0.63)	3.2 (1.92)
Peak value (score)	8.5 (5.57)	9.8 (7.57)	9.4 (5.46)
Duration (days)	6.3 (2.87)	5.8 (2.79)	6.0 (3.0)

SD, Standard deviation.

Time to Peak = Number of days from Day 0 until the peak is observed.

Peak value = the highest number of individual symptoms grade 1 or higher on a given Day between Day 0 (post challenge) to Day 8.

Duration = Time in days from the Day when a symptom of grade 1 or higher is first observed to the Day when a symptom of grade 1 or higher is last observed.

Table includes only volunteers with at least one symptom grade 1 or higher.