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. 2016 Dec 9;11(12):e0166486. doi: 10.1371/journal.pone.0166486

Fig 1. CpG methylation in whole blood DNA of heavy smokers.

Fig 1

(A) Manhattan plot of p-value associations between smoking and CpG methylation with genome-wide significance level (red line, p = 1.5x10-7). CpGs in genes that were also examined in individual cell types are labeled. Blue points represent 1st time reported smoking CpGs. (B) AHRR cg05575921 methylation level by quartiles of self-reported cigarettes per day. (C) AHRR cg05575921 methylation level by quartiles of cumulative smoking in pack-year.