Fig 6. Ectopic miR-182 expression or c-Met siRNA transfection downregulates multiple cell signaling pathways.

RPE cells were transfected with miR-182 or c-Met specific siRNA and then analyzed by Western blotting. (A) miR-182 downregulated expression of c-Met, p-Met and p-Akt, but not total Akt or ERK1/2. (B) c-Met specific siRNA downregulated expression of c-Met, p-Met and p-Akt, but not total Akt or ERK1/2.