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. 2016 Dec 9;11(12):e0167813. doi: 10.1371/journal.pone.0167813

Fig 3. BMDC Inhα-/- showed poor allogeneic CD4+ CD25- Foxp3- T cells stimulation capacity.

Fig 3

Unstimulated and 24h LPS-stimulated CD11c+ cells were sorted at day 6 of culture and were co-cultivated with CD4+ CD25- Foxp3- T cells from Foxp3-GFP KI Balb/c. At day 5, proliferation of T cells was measured by CTV dilution. A. Representative dot plot of CTV dilution from Inhα+/+ BMDC (left) and Inhα-/- BMDC (right). B. Graphs of divided T cells at 1:10 ratio represent mean ± SEM of 4 independent experiments. Statistical significance was determined by a two-tailed unpaired Student t-Test. *p≤0.05.