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. 2016 Nov 23;5(11):e117. doi: 10.1038/emi.2016.115

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The results of phylogenetic analyses based on the nucleotide sequences of the currently available complete genomes (A), fiber 1 (B), fiber 2 (C) and hexon (D) gene sequences of FAdV-4 isolates and representative genes of other FAdV species. The trees were generated by the maximum-likelihood method with bootstrap tests of 1000 replicates using the MEGA 6.06 software. Bootstrap values are presented at key nodes. The scale bars indicate the nucleotide substitutions per site. Filled circles indicate HHS-inducing FAdV-4 strains. Open circles indicate non-HHS-inducing strains. Hepatitis-hydropericardium syndrome (HHS).