Skip to main content
. 2016 Dec 9;11(12):e0167894. doi: 10.1371/journal.pone.0167894

Fig 2. Sphingosine 1-phosphate induces matriptase activation without inducing prostasin zymogen activation.

Fig 2

Human mammary epithelial cells 184 A1N4 were treated with fresh medium, which contains sphingosine 1-phosphate derived from FBS, for the indicated times. The cells were harvested and analyzed by Western blot for matriptase species (A) and prostasin (B.). The size of matriptase-HAI-1 complex (MTP-HAI-1) and prostasin-HAI-1 complex (Pros.-HAI-1) were indicated. The experiment was conducted twice with the same profile observed. Representative data are shown.