Fig 6. Caco-2 cells maintain high levels of prostasin zymogen activation regardless of matriptase expression.

Parental Caco-2 cells (WT, lanes 1) and Caco-2 variants with reduced (KD, lanes 3) or ablated (KO, lanes 3) HAI-2 expression were analyzed by Western blot for matriptase species (A.) and prostasin species (B.). The different forms of prostasin are indicated. The immunblot analysis was conducted at least twice with the same profile observed. Representative data are shown.